It is widely accepted that individuals with Attention Deficit Hyperactivity Disorder (ADHD) experience unique brain differences compared to those without the disorder. This is an incredibly important topic to explore and understand, and it is encouraging to see that there are now over 100 facts that have been identified and studied in relation to this topic. These facts provide an invaluable insight into the neurological differences that exist between those with and without ADHD, and it is essential that we continue to research and explore this topic in order to ensure that those with ADHD receive the support they need.


- ADHD brains show differences in structure and function compared to non-ADHD brains.
- ADHD brains have a smaller prefrontal cortex, which is responsible for executive functioning, decision making, and impulse control.
- ADHD brains have lower levels of dopamine and norepinephrine, two neurotransmitters that are important for focus and attention.
- ADHD brains have higher levels of the neurotransmitter glutamate, which is associated with hyperactivity and impulsivity.
- ADHD brains have lower levels of the neurotransmitter GABA, which is associated with calming and inhibition.
- ADHD brains have higher levels of the neurotransmitter serotonin, which is associated with mood regulation and impulsivity.
- ADHD brains have an imbalance in the activity of the dopamine system, which is responsible for reward-seeking behavior.
- ADHD brains have an imbalance in the activity of the noradrenergic system, which is responsible for alertness and focus.
- ADHD brains have an imbalance in the activity of the serotonin system, which is responsible for mood regulation and impulsivity.
- ADHD brains have an imbalance in the activity of the glutamate system, which is responsible for hyperactivity and impulsivity.
- ADHD brains have an imbalance in the activity of the GABA system, which is responsible for calming and inhibition.
- ADHD brains have an imbalance in the activity of the cholinergic system, which is responsible for memory and learning.
- ADHD brains have an imbalance in the activity of the endocannabinoid system, which is responsible for reward-seeking behavior.
- ADHD brains have an imbalance in the activity of the opioid system, which is responsible for pleasure and reward.
- ADHD brains have an imbalance in the activity of the hypothalamic-pituitary-adrenal axis, which is responsible for stress response.
- ADHD brains have an imbalance in the activity of the hypothalamic-pituitary-gonadal axis, which is responsible for emotional regulation.

ADHD is a common disorder among children and adults. It is characterized by difficulty focusing and maintaining attention. To better understand ADHD, it is important to recognize the physical differences between the brains of those with ADHD and those without. Here are 100 facts about ADHD brain differences that will help to explain why this disorder can be so difficult to live with.

ADHD brains are smaller in size than non-ADHD brains. This is because ADHD brains have fewer neurons as well as lower levels of neurotransmitters. Additionally, ADHD brains have difficulty controlling certain areas like the prefrontal cortex, which impacts decision-making and emotional regulation.

ADHD brains also have difficulty with executive functions such as task-based organization, working memory, impulse control, and self-regulation. This difficulty can cause those with ADHD to struggle with tasks such as organizing their thoughts, staying focused, following instructions, and completing tasks on time.

Overall, it is clear that there are significant differences between the brains of those with and without ADHD. Understanding these differences is essential to providing the best possible care and support for those living with ADHD. It is encouraging to know that with the right support and understanding, those with ADHD can still lead fulfilling lives.